The Alinari Lab at the Ohio State University (OSU) is seeking highly motivated and successful individuals to study the lymphoma-immune cells crosstalk, to identifying therapeutic strategies that trigger potent immunogenic cell death in lymphoma, and to develop novel immunotherapies for lymphoma.

Responsibilities:

• Performing with a variety of complex molecular biology techniques, including protein/DNA/RNA isolations, Western blots, Immunoprecipitation, PCR techniques, etc.

• Immune cell transfection and viral transduction using lentivirus

• Gene editing using CRISPR-Cas9

• Spectral flow cytometry and cell sorting including preparing, executing, and analyzing samples

• Performing a variety of cell culture techniques including: mammalian cell culture, primary cell culture, and processing tissue (human and murine) into single cell suspensions

• Processing human blood samples, and isolating human immune cell subtypes

• Performing data analysis and other statistical techniques on sample data, including processing flow data, sequencing, and using various statistical software.

• Bacterial work including transformation and plasmid isolations

• Assisting or executing animal studies including drug delivery, IVIS imaging, tissue harvesting, etc.

• Assisting with writing and figure generation for manuscripts at the direction of the supervisor

• Training other staff on techniques and protocols, including generating new protocols as needed

• Independently troubleshooting assays and protocols

• Taking inventory and assisting with ordering and restocking lab supplies

• Maintaining lab equipment

Required Education/Experience:

• A Doctoral degree in an appropriate discipline such as immunology or cancer biology is required.

• Requires successful completion of a background check; qualified candidates may be asked to complete a pre-employment physical including a drug screen.

Preferred Qualifications:

• Previous lab experience including working with cancer cells/immunological assays

• Multiple first author publications

Salary Range:

$56,484 - $68,604 per the NIH scale